The complete guide to marijuana and the brain (2017)

The complete guide to marijuana and the brain (2017)

Reference list © 2010 Allen Institute for Brain Science. Allen Human Brain Atlas. Available from: human.brain-map.org Gardner, E. L. (2005). Endocannabinoid signaling system and brain reward: emphasis on dopamine. Pharmacology Biochemistry and Behavior, 81(2), 263-284. Filbey, F. M., Schacht, J. P., Myers, U. S., Chavez, R. S., & Hutchison, K. E. (2009). Marijuana craving in the brain. Proceedings of the National Academy of Sciences, 106(31), 13016-13021. Lubman, D. I., Cheetham, A., & Yücel, M. (2015). Cannabis and adolescent brain development. Pharmacology & therapeutics, 148, 1-16. Batalla, A., Bhattacharyya, S., Yücel, M., Fusar-Poli, P., Crippa, J. A., Nogué, S., ... & Martin-Santos, R. (2013). Structural and functional imaging studies in chronic cannabis users: a systematic review of adolescent and adult findings. PloS one, 8(2), e55821. Lisdahl, K. M., Gilbart, E. R., Wright, N. E., & Shollenbarger, S. (2013). Dare to delay? The impacts of adolescent alcohol and marijuana use onset on cognition, brain structure, and function. Frontiers in Psychiatry, 4. Campolongo, P., Roozendaal, B., Trezza, V., Hauer, D., Schelling, G., McGaugh, J. L., & Cuomo, V. (2009). Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory. Proceedings of the National Academy of Sciences, 106(12), 4888-4893. Patel, S., Cravatt, B. F., & Hillard, C. J. (2005). Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala. Neuropsychopharmacology, 30(3), 497-507. Phan, K. L., Angstadt, M., Golden, J., Onyewuenyi, I., Popovska, A., & De Wit, H. (2008). Cannabinoid modulation of amygdala reactivity to social signals of threat in humans. Journal of Neuroscience, 28(10), 2313-2319. Chhatwal, J. P., Davis, M., Maguschak, K. A., & Ressler, K. J. (2005). Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear. Neuropsychopharmacology, 30(3), 516-524. Tan, H., Lauzon, N. M., Bishop, S. F., Bechard, M. A., & Laviolette, S. R. (2009). Integrated cannabinoid CB1 receptor transmission within the amygdala–prefrontal cortical pathway modulates neuronal plasticity and emotional memory encoding. Cerebral cortex, 20(6), 1486-1496. Broyd, S. J., van Hell, H. H., Beale, C., Yücel, M., & Solowij, N. (2016). Acute and chronic effects of cannabinoids on human cognition—a systematic review. Biological psychiatry, 79(7), 557-567. Gonzalez, R. (2007). Acute and non-acute effects of cannabis on brain functioning and neuropsychological performance. Neuropsychology review, 17(3), 347-361. Weiland, B. J., Thayer, R. E., Depue, B. E., Sabbineni, A., Bryan, A. D., & Hutchison, K. E. (2015). Daily marijuana use is not associated with brain morphometric measures in adolescents or adults. Journal of Neuroscience, 35(4), 1505-1512. Sami, M. B., Rabiner, E. A., & Bhattacharyya, S. (2015). Does cannabis affect dopaminergic signaling in the human brain? A systematic review of evidence to date. European Neuropsychopharmacology, 25(8), 1201-1224. Orr, J. M., Paschall, C. J., & Banich, M. T. (2016). Recreational marijuana use impacts white matter integrity and subcortical (but not cortical) morphometry. NeuroImage: Clinical, 12, 47-56. Yücel, M., Solowij, N., Respondek, C., Whittle, S., Fornito, A., Pantelis, C., & Lubman, D. I. (2008). Regional brain abnormalities associated with long-term heavy cannabis use. Archives of general psychiatry, 65(6), 694-701. Battistella, G., Fornari, E., Annoni, J. M., Chtioui, H., Dao, K., Fabritius, M., ... & Giroud, C. (2014). Long-term effects of cannabis on brain structure. Neuropsychopharmacology, 39(9), 2041-2048. Lorenzetti, V., Solowij, N., Fornito, A., Ian Lubman, D., & Yucel, M. (2014). The association between regular cannabis exposure and alterations of human brain morphology: an updated review of the literature. Current Pharmaceutical Design, 20(13), 2138-2167. Crean, R. D., Crane, N. A., & Mason, B. J. (2011). An evidence based review of acute and long-term effects of cannabis use on executive cognitive functions. Journal of addiction medicine, 5(1), 1. Hanson, K. L., Winward, J. L., Schweinsburg, A. D., Medina, K. L., Brown, S. A., & Tapert, S. F. (2010). Longitudinal study of cognition among adolescent marijuana users over three weeks of abstinence. Addictive behaviors, 35(11), 970-976. Han, J., Kesner, P., Metna-Laurent, M., Duan, T., Xu, L., Georges, F., ... & Liu, Q. (2012). Acute cannabinoids impair working memory through astroglial CB 1 receptor modulation of hippocampal LTD. Cell, 148(5), 1039-1050. Solowij, N., & Battisti, R. (2008). The chronic effects of cannabis on memory in humans: a review. Current drug abuse reviews, 1(1), 81-98. G Bossong, M., Jager, G., Bhattacharyya, S., & Allen, P. (2014). Rest of list wouldn't fit

Marijuana and the brain

Marijuana and the brain

Oregon recently joined only three other states to legalize recreational marijuana. As consumption of the plant's products becomes more a mainstream activity, its health benefits and risks will be at the forefront of policy discussions. Dr. Nephi Stella explains the role marijuana plays in cutting edge neuroscience research.

The Pharmacology of Cannabis Cannabinoids and Terpenes by Dr. Ethan Russo

The Pharmacology of Cannabis Cannabinoids and Terpenes by Dr. Ethan Russo

Understanding the Pharmacology of Cannabis. Dr. Ethan Russo speaks about the science of Cannabis Cannabinoids and Terpenes at the Cannabis Hemp Conference and Expo (CHCE). Ethan Russo, MD, is a board-certified neurologist, psychopharmacology researcher, and Medical Director of PHYTECS, a biotechnology company researching and developing innovative approaches targeting the human Endocannabinoid system. Previously, from 2003-2014, he served as Senior Medical Advisor and study physician to GW Pharmaceuticals for numerous Phase I-III clinical trials of Sativex® for pain and MS, and initial studies of Epidiolex® for intractable epilepsy. He graduated from the University of Pennsylvania (Psychology) and the University of Massachusetts Medical School, before residencies in Pediatrics in Phoenix, Arizona and in Child/Adult Neurology at the University of Washington. He was a clinical neurologist in Missoula, Montana for 20 years. He has held faculty appointments in Pharmaceutical Sciences at the University of Montana, in Medicine at the University of Washington, and as visiting professor, Chinese Academy of Sciences. He is a Past-President of the International Cannabinoid Research Society, and former Chairman of the International Association for Cannabinoid Medicines. He serves on the Scientific Advisory Board for the American Botanical Council. He has published several books, numerous book chapters, and over forty articles in neurology, pain management, cannabis, and ethnobotany. He has consulted or lectured on these topics in more than 30 US states and 30 countries. The NEST, University of British Columbia May 6-7th, 2017 Vancouver, Canada CannabisHempConference.com

What Happens If You Damage The Hippocampus | The Great Courses

What Happens If You Damage The Hippocampus | The Great Courses

Try a free trial of The Great Courses Plus and watch the course here: https://www.thegreatcoursesplus.com/special-offer?utm_source=US_OnlineVideo&utm_medium=SocialMediaEditorialYouTube&utm_campaign=145762 This clip from Dr. Robert Sapolsky's course Stress and Your Body will open your eyes to what happens if you damage your hippocampus. Don’t forget to subscribe to our channel – we are adding new videos all the time! https://www.youtube.com/subscription_center?add_user=TheGreatCourses

The science of psilocybin and its use to relieve suffering

The science of psilocybin and its use to relieve suffering

Leading psychopharmacologist Roland Griffiths discloses the ways that psychedelic drugs can be used to create spiritually meaningful, personally transformative experiences for all patients, especially the terminally ill.

Is Marijuana Unhealthy? An In-Depth Look at the Research

Is Marijuana Unhealthy? An In-Depth Look at the Research

This video reviews over 20 studies on the topic to determine which myths and claims about its harms and benefits are valid. - Links and Sources - https://www.patreon.com/micthevegan https://www.facebook.com/micthevegan https://www.instagram.com/micthevegan - @micthevegan https://plantspace.org TIY Tiny House Channel: https://www.youtube.com/channel/UCYhthOBh4_459pAge62at8g DEA schedule 1: https://www.dea.gov/druginfo/ds.shtml NIH write-up on the topic: http://tinyurl.com/q3fyhqh Lung Cancer Main Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262725/pdf/nihms607200.pdf Wood Stoves and Lung cancer: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002194/pdf/ehp-118-1743.pdf Heavy Users 2 fold risk lung cancer study: https://www.ncbi.nlm.nih.gov/pubmed/23846283 Heavy Users 5.7 fold lung cancer risk study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516340/pdf/ukmss-2178.pdf Estimate of Average Cigs Per day: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1117323/ Smoke Danger Comparison Study (Also anti-cancer quote): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1277837/pdf/1477-7517-2-21.pdf Vaporization Reduces Cig Toxins: http://annals.org/aim/article/2599869/nicotine-carcinogen-toxin-exposure-long-term-e-cigarette-nicotine-replacement 108/111 other compounds removed in vapor: http://www.canorml.org/healthfacts/jcantgieringervapor.pdf Mental Illness Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341491/pdf/S0033291716003172a.pdf "acutely raises dopamine levels in the striatum." Study 2014: http://www.sciencedirect.com/science/article/pii/S0278584613002340?via%3Dihub Dopamine increase in subjects: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816196/pdf/emss-66024.pdf Deficit in striatal dopamine release Study 2016: http://www.nature.com/mp/journal/v22/n1/full/mp201621a.html?foxtrotcallback=true" Dopamine process alternations in young starters: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314125/pdf/nihms346717.pdf 9% Addiction Rate Study: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21145178/ CDC Alcohol Deaths: https://www.cdc.gov/alcohol/fact-sheets/alcohol-use.htm" CDC Alcohol Poisoning: https://www.cdc.gov/vitalsigns/alcohol-poisoning-deaths/index.html French Study on Traffic Accidents: http://www.tandfonline.com/doi/abs/10.1080/15389580701737561?scroll=top&needAccess=true&journalCode=gcpi20 No Increased Accidents Under the Influence: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893634/pdf/jsad56.pdf Drunk driving = nearly 1/3 of all traffic deaths. https://www.cdc.gov/motorvehiclesafety/impaired_driving/impaired-drv_factsheet.html 1 in 4 traffic deaths is now due to cell phones: http://www.nsc.org/NewsDocuments/2014-Press-Release-Archive/3-25-2014-Injury-Facts-release.pdf Violence from Alcohol: http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.486.6496&rep=rep1&type=pdf IQ Adolescents Use Study: http://www.pnas.org/content/109/40/E2657.full.pdf Alcohol Damages but doesn't kill brain cells: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796092/ Infant Risks and Breast Milk: http://tinyurl.com/oq48hpz Reduction in Childhood Seizures Study: https://www.ncbi.nlm.nih.gov/pubmed/24237632/ Featured Video about Seizures: https://www.youtube.com/watch?v=LmlpoX5EGU0 Featured Video about Parkinson's: https://www.youtube.com/watch?v=zNT8Zo_sfwo Parkinson's Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436333/pdf/can.2017.0002.pdf PSTD Study Underway: http://tinyurl.com/zsuaxz5 STD Risk Increased: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827335/pdf/nihms762992.pdf

The Amazing Power of Your Mind - A MUST SEE!

The Amazing Power of Your Mind - A MUST SEE!

With nearly 60,000 thoughts per day, you’re bound to have plenty of negative ones, right? What you may not realize is the power you hold when it comes to the anxious thoughts and feelings you have on a daily basis. Millions of people suffer from the effects of anxiety as they allow their subconscious minds run their lives. The key to overcoming anxiety is to realize that YOU ARE IN CONTROL. In other words, if you are able to create your anxious responses to situations, you are also able to take them away. The first step to a better life is understanding that your response to scenarios is what causes your anxiety and stress, rather than the situations themselves causing your reactions. Discover the ins and outs of this explosive scientific discovery in this short informative video brought to you by Jeremy Bennett. (For more info on Jeremy Bennett please like his Facebook page here -- http://www.facebook.com/jeremybennettfanpage...)

10 Secrets Marijuana Smokers Won't Tell You

10 Secrets Marijuana Smokers Won't Tell You

Get Infinite Waters Clothing Now: https://goo.gl/JYV7TV Feel Alive by Ralph Smart. Book Out Now: https://goo.gl/s2SSKc Personal Consultations: https://goo.gl/KVheJF The Website - Exclusive Content: http://www.ralphsmart.com Instagram: https://www.instagram.com/infinitewaters Facebook: https://www.facebook.com/infinitewatersworld/ https://www.facebook.com/ralphsmart Follow on Twitter: https://twitter.com/infinitewaters Follow on Tumblr https://tumblr.com/infinitewatersworld

Brain Reward: Understanding How the Brain Responds to Natural Rewards and Drugs of Abuse

Brain Reward: Understanding How the Brain Responds to Natural Rewards and Drugs of Abuse

You can grow new brain cells. Here's how | Sandrine Thuret

You can grow new brain cells. Here's how | Sandrine Thuret

Can we, as adults, grow new neurons? Neuroscientist Sandrine Thuret says that we can, and she offers research and practical advice on how we can help our brains better perform neurogenesis—improving mood, increasing memory formation and preventing the decline associated with aging along the way. TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design -- plus science, business, global issues, the arts and much more. Find closed captions and translated subtitles in many languages at http://www.ted.com/translate Follow TED news on Twitter: http://www.twitter.com/tednews Like TED on Facebook: https://www.facebook.com/TED Subscribe to our channel: http://www.youtube.com/user/TEDtalksDirector

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