Developed and produced by http://www.MechanismsinMedicine.com Animation Description: Bipolar Disorder encompasses a wide spectrum of symptoms and is classified according to the types of mood episodes exhibited, including: manic, hypomanic, major depressive and mixed episodes. Bipolar I disorder involves a manic or mixed episode in contrast to Bipolar II disorder, which involves at least one major depressive episode and at least one hypomanic episode, but no full manic or mixed episodes. Bipolar Disorder should be differentiated from Major Depressive Disorder (MDD), which is diagnosed when a patient experiences one or more major depressive episodes without any lifetime episodes of hypomania or mania. Depicted here is a life chart (or mood chart), which follows the patient's lifetime history of mood episodes. This permits the identification of mood episodes that are the most prevalent and important to prevent. In this patient, as with many patients with bipolar disorder, depressive episodes become the more prominent aspect of the illness as the person ages. Several morphometric differences have been observed in the brains of Bipolar Disorder patients relative to healthy subjects. White matter hyperintensities and reduction in grey matter volume, identified with MRI, have been described in patients with Bipolar Disorder. Increased ventricular size and decreased frontal cortical area volumes may also be observed in Bipolar Disorder patients. The pathophysiology of Bipolar Disorder encompasses environmental, behavioural, neuronal, cellular, and molecular levels. At the molecular level, aberrant signaling cascades alter synaptic plasticity. Strong evidence supporting the importance of second messenger signaling has come from studying the targets of mood stabilizing drugs such as lithium. GSK-3 and IP3 signaling cascades are known to mediate axonogenesis, synaptogenesis, neuronal growth and cone spreading. Other downstream effects may also be involved. The heritability of bipolar disorder is around 80%. Monozygotic twins are reported to have a higher incidence of developing Bipolar Disorder, approximately 40%, whereas the incidence is only 10% in dizygotic twins. Although the process of developing bipolar disorder likely arises from complex interactions between genes and environmental factors, the specific genes that contribute to this risk are not known with certainty. Variations of several genes have been identified as potential contributors to the pathophysiology of bipolar disorder. Among the identified genes are those associated with serotonin signaling (SLC6A4, TPH2), dopamine signaling (SLC6A3, DRD4), glutamate transmission (DAOA, DTNBP1), and cell maintenance and growth (NRG1, BDNF, DISC1). The most significant environmental triggers of mood episodes among patients with bipolar disorder include use of drugs with mood-altering properties, changes in circadian rhythm, and life stressors. Successful management of bipolar disorder requires particular attention to minimizing the effects of these influences. It is also available on http://www.MDPracticeGuide.com - wholly CME guideline resource dedicated to the needs of busy, practice-based physicians, which spans multiple therapeutic areas.
NICE Guidance for Schizophrenia in General Practice
Delirium is frequently found in critically ill adults, affecting patient outcomes both during and after the intensive care unit (ICU) stay. This webcast will address an important component of the ABCDEF Bundle, Delirium: Assess Prevent and Manage, for clinicians seeking to liberate their patients from the ICU and improve their outcomes. During this session, Michele Balas, PhD, RN, APRN-NP, CCRN, and John Devlin, PharmD, FCCM, FCCP, will discuss the importance of routine delirium screening in the critically ill and integrated strategies to boost the routine use of a validated instrument such as the confusion assessment method for the ICU (CAM-ICU) or the intensive care delirium checklist (ICDSC). The speakers will also address frequently asked questions about delirium management, and the presentation will conclude with a question-and-answer segment. Learning Objectives •Recognize the importance of routine delirium screening in the ICU using the CAM-ICU or the ICDSC •Identify modifiable risk factors for delirium in the critically ill •Apply non-pharmacologic strategies to reduce the burden of delirium in the critically ill •Understand the limited role that medication-focused interventions currently have in treating delirium in the ICU
In this video we discuss the symptoms of schizophrenia and the dopamine hypothesis of its pathogenesis. We also discuss the mechanism by which the antipsychotic drugs produce remission from the psychotic symptoms.
This alternative therapy employs vitamins, minerals, and amino acids to create optimum nutritional content for the body, as well as the right environment and equilibrium. Like most alternative medicine techniques, orthomolecular medicine targets a wide range of conditions. [depression, bipolar, adhd, schizophrenia, add, addiction, alcoholism, drug addiction...] Orthomolecular medicine was developed by Linus Pauling, Ph.D., winner of two Nobel prizes, in 1968. It is designed to enable individuals to reach the apex of health and the peak of their performance by utilizing only naturally occurring substances (e.g. vitamins, minerals, enzymes, trace elements, co-enzymes). The proper balance of these substances in the body is the key to reaching physical, mental, and emotional health and stability. Orthomolecular medicine can be used therapeutically to treat diseases such as cancer and AIDS, or preventatively to impede the progress of degenerative disease and aging. When all is said and done, however, the main objective of orthomolecular medicine is to help the patient reach an optimal level of health; his or her self-esteem will probably improve in the process. Although orthomolecular medicine did not fully develop into a therapy until the late 1960's when Pauling coined the term "orthomolecular," the premise behind this practice originated in the 1920's, when vitamins and minerals were first used to treat illnesses unrelated to nutrient deficiency. It was discovered that vitamin A could prevent childhood deaths from infectious illness, and that heart arrhythmia (irregular heartbeat) could be stopped by dosages of magnesium. Hard scientific evidence supporting nutritional therapy did not emerge, however, until the 1950's, when Abram Hoffer, M.D., and Humphrey Osmond, M.D., began treating schizophrenics with high doses of vitamin B3 (niacin). As a consequence of their studies, it was revealed that niacin, in combination with other medical treatments, could double the number of recoveries in a one-year period. Eventually, it was determined that malnutrition and consumption of refined, empty-calorie foods such as white bread and pastries and overconsumption of sugar could yield disease and psychiatric disorders. It became apparent that a person's diet was an overwhelmingly integral part of his or her health and well-being. Further studies showed that decreased intake of dietary fiber, bran, minerals, and complex carbohydrates was prevalent in patients with certain forms of mental illness, accompanied by a loss of vitamins and an increase in dietary fat. Biochemical individual is a main principle of orthomolecular medicine. This principle was elucidated by Roger J. Williams, Ph.D. This principle is quite simple: every living organism is unique! Furthermore, each individual requires different relative amounts of nutrients for his or her satisfaction and optimal level of health. The government sets a minimum recommended daily allowance (RDA) which is supposed to be adequate for all individuals. However, many may need to exceed the RDA as well as the recommended 2,000 calorie diet in order to prevent severe deficiency disease. Thus, RDA values are not perfect guidelines for everyone. Several studies have proven the existence of biochemical individuality. For example, studies of guinea pigs showed a twentyfold variation in their requirement for vitamin C. A study conducted with human subjects revealed that children have varying needs for vitamin B6.
This video “Alcohol and Delirium” is part of the Lecturio course “Psychiatry” ► WATCH the complete course on http://lectur.io/alcohol ► LEARN ABOUT: - Mechanism of action - GABA receptors and the effects of alcohol - Metabolism of alcohol - People of Asian descent and alcohol - Screening tests for alcohol use disorder - CAGE questioner - Alcohol intoxication - Blood levels of alcohol and behavioral effects - Treatment of alcohol related disorders ... ► THE PROF: Dr. Farrell is a Harvard Medical School faculty member and board certified psychiatrist with a private practice in Boston. She has experience in patient care, teaching and in treating psychological disorders in various settings, including the Emergency Department, inpatient units and outpatient settings. ► LECTURIO is your single-point resource for medical school: Study for your classes, USMLE Step 1, USMLE Step 2, MCAT or MBBS with video lectures by world-class professors, recall & USMLE-style questions and textbook articles. Create your free account now: http://lectur.io/alcohol ► INSTALL our free Lecturio app iTunes Store: https://app.adjust.com/z21zrf Play Store: https://app.adjust.com/b01fak ► READ TEXTBOOK ARTICLES related to this video: http://lectur.io/alcohollibrary ► SUBSCRIBE to our YouTube channel: http://lectur.io/subscribe ► WATCH MORE ON YOUTUBE: http://lectur.io/playlists ► LET’S CONNECT: • Facebook: https://www.facebook.com/lecturio.medical.education.videos • Instagram: https://www.instagram.com/lecturio_medical_videos • Twitter: https://twitter.com/LecturioMed
This video contains extremely raw graphic footage of myself in a full blown psychotic episode, shot whist on a psychiatric hospital ward it will give in insight into the mind of someone suffering Bipolar Affective Disorder Type 1 whist in a full mania and with psychosis. Lee James Artist is a full time artist and co-owner of Love Upcycled www.loveupcycled.com Twitter - https://twitter.com/LeeJamesArtist Facebook - https://www.facebook.com/lordbaalnox Subscribe here - https://www.youtube.com/channel/UCRPzTaWgvujvusC5E5s7Pfw
Take Dr. Berg's Advanced Evaluation Quiz: http://bit.ly/EvalQuiz Your report will then be sent via email analyzing 104 potential symptoms, giving you a much deeper insight into the cause-effect relationship of your body issues. It's free and very enlightening. Dr. Berg talks about whats really behind leaky gut. It is scurvy of the colon. A lack of vitamin C can cause a loss of collagen in the lining of the intestines thus making the gaps open and allow undigested proteins to enter. DR. BERG'S VIDEO BLOG: http://www.drberg.com/blog FACEBOOK: http://www.facebook.com/DrEricBerg TWITTER: http://twitter.com/DrBergDC YOUTUBE: https://www.youtube.com/user/drericbe... ABOUT DR. BERG: http://www.drberg.com/dr-eric-berg/bio DR. BERG'S SEMINARS: http://www.drberg.com/seminars DR. BERG'S STORY: http://www.drberg.com/dr-eric-berg/story DR. BERG'S CLINIC: https://www.drberg.com/dr-eric-berg/c... DR. BERG'S HEALTH COACHING TRAINING: http://www.drberg.com/weight-loss-coach DR. BERG'S SHOP: http://shop.drberg.com/ DR. BERG'S REVIEWS: http://www.drberg.com/reviews The Health & Wellness Center 4709 D Pinecrest Office Park Drive Alexandria, VA 22312 703-354-7336 Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. The Health & Wellness, Dr. Berg Nutritionals and Dr. Eric Berg, D.C. are not liable or responsible for any advice, course of treatment, diagnosis or any other information, services or product you obtain through this video or site.
http://www.cre8-health.com Dr Mercola with Dr Saul discuss on the phone how drugs are not nutrients and that the body does not understand drugs. The body understand nutrients and vitamins. Especially B3 which can cause elevation in mood in depressed patients and even reduce ADHD tendencies in infants and adults as well as helping with the cure of schizophrenia and it also helps dramatically with chronic arthritis patients. - Niacin B3 Flushing - Niacinamide B3 Non-Flushing - Inositol-hexaniacinate B3 Non-Flushing http://www.facebook.com/cre8health
This video describes Paranoid Personality Disorder. Paranoid Personality Disorder is characterized by a pervasive pattern of suspiciousness and distrust of others. Individuals with Paranoid Personality Disorder will often question the loyalty of others, believe others are trying to harm them, and are reluctant to confide in people. They sometimes see demeaning aspects in benign comments and behaviors. Individuals with Paranoid Personality Disorder tend hold grudges and have difficultly forgiving perceived wrongs. Individuals with Paranoid Personality Disorder who are married tend to question the fidelity of their partners. Paranoid Personality Disorder are in Cluster A of the personality disorders in the Diagnostic and Statistical Manual (DSM) along with Schizoid Personality Disorder and Schizotypal Personality Disorder. Brief psychosis can occur with Paranoid Personality Disorder, which can make diagnosing this disorder more difficult due to association of psychosis with Schizophrenia, Major Depressive Disorder, and Bipolar Disorder. Disorders that are comorbid with Paranoid Personality Disorder include Major Depressive Disorder, Obsessive Compulsive Disorder, Substance Use Disorder, Agoraphobia, Schizoid Personality Disorder, Schizotypal Personality Disorder, Avoidant Personality Disorder, Narcissistic Personality Disorder, and Borderline Personality Disorder. The prevalence of Paranoid Personality Disorder in the population is about 2% - 4%.