Nitric Oxide Supplements: What is Agmatine?

Nitric Oxide Supplements: What is Agmatine?

Agmatine is a nitric oxide supplement - there is no evidence to support any of the performance claims made for this supplement at this time. See all our nitric oxide supplement videos: https://www.youtube.com/playlist?list=PLk2mWkuRCTaU2XwyMSiMlRuZLBVq1Sr7n Referenced links: Agmatine review: http://www.ultimatefatburner.com/bodybuilding/nitric-oxide-supplements-what-is-agmatine.html Citrulline review: http://www.ultimatefatburner.com/bodybuilding/citrulline-nitric-oxide.html Arginine review: http://www.ultimatefatburner.com/bodybuilding/does-arginine-work.html Hey guys, Paul from UltimateFatBurner here. Today we’re going to talk about agmatine. You may have seen Agmatine included in some of the newer pre workout and strength promoting supplements – nitric oxide supplements - along with claims about how well it works for skin-tearing pumps, super-intense workouts and all the usual over-the-top nonsense we’re used to seeing in sport supplement advertising. So let’s talk about agamatine – what do we know about it, does it work, should you try it and so on. I’m going to answer these questions in 10 seconds. Stick around – don’t go anywhere! What is Agmaine? Agamatine is a metabolite of arginine – its technical name is decarbolyzed arginine - and a promising and interesting compound, although there is very little clinical data on it. What do we know about so far, as far as its use a sports performance and pump product? Well, here are the 4 things you need to know about agmatine… 1) There is no clinical evidence either to support or disprove agmatine's use a BB or sports performance supplement. Zero. Zip. Nien. Nyet. Nada.Nothing. So all these various claims are essentially being pulled out of the air. Agamine may provide to be a great supplement for body builders or may not, but as of right now, we really don’t know. 2) There is research that suggests that agmatine has a NO-boosting vasodilating effect but these animal studies or ex-vivo / in-vitro laboratory studies, not human based studies. How it works isn't entirely clear yet, although it may stimulate the expression of one of the enzymes required for the body to make more NO. 3) Agmatine is not a nitric oxide precursor – in other words, it does not appear to work in a smiliar manner to arginine, despite being an arginine metabolite. In fact, it appears to be a mild inhibitor of NOSs – the family on enzymes required to convert arginine into NO. 4) It's non-toxic and appears to be safe, and can be justified under DSHEA and most supplement laws. And essentially, that’s a big picture overview on what know about agamatine when it comes to its use as a body building supplement. Not a lot, is it? OK, a couple of comments before I wrap up this video… Absence of evidence isn’t the same as evidence of absence.” In other words, even if there’s no evidence to support its use as a “pump” or sports performance product, it may nonetheless have some health/wellness value; for instance there is one small study on its use for major depressive disorder. Additionally, anecdotal evidence – and by anecdotal I mean “word of mouth” commentary - suggests that most (although definitely not all) users think it does work as advertised. So what’s the bottom line on agmatine at this point? Its use as a sports performance is entirely based on anecdotal evidence. If you like the pump and it works for you, great! Just as long as you understand that there’s no established science behind the claims made for it. A stronger argument can definitely made for the use of arginine or citrulline as a nitric oxide supplement, if you’re more interested in using products that have some supporting science behind them. Personally, this is where I’m sticking… I don’t find the agmatine pump to be as pronounced. But maybe you feel differently? If you’ve used agmatine or a product containing it, please share you experience and leave your comments below – I know I’d love to hear them as would our viewers. Oh, and before I forget… If you’d like to take a moment to subscribe to this channel, that would be great… it would really help me out. Thanks for watching and I hope to see again really soon! YouTube Video link: https://youtu.be/ntQBQ1I2HIU

Agmatine and Pre JYM

Agmatine and Pre JYM

For all my training advice go to: www.jimstoppani.com In this video I go over Agmatine and Pre JYM

Burning Fat Fast and Building Stamina | Why I Take Agmatine Sulfate

Burning Fat Fast and Building Stamina | Why I Take Agmatine Sulfate

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Guide to Agmatine - eSupplements.com

Guide to Agmatine - eSupplements.com

Guide to Agmatine - eSupplements.com http://www.esupplements.com/article/agmatine-benefits/

Agmatine - General Info and Personal Experience

Agmatine - General Info and Personal Experience

The title says it all. Sources and Further Reading: https://www.ncbi.nlm.nih.gov/pubmed/11108990 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922054/ https://www.ncbi.nlm.nih.gov/pubmed/9918557 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1217329/pdf/8645212.pdf

Glutamine and Agmatine Safety And Efficacy--Ask The Machine

Glutamine and Agmatine Safety And Efficacy--Ask The Machine

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Agmatine Sulfate Review - Does it Increase Nitric Oxide?

Agmatine Sulfate Review - Does it Increase Nitric Oxide?

https://www.bestpricenutrition.com/pages/search-results-page?q=agmatine+sulfate - John talks about whether agmatine sulfate really increases nitric oxide. Galgano F, et al. Focused review: agmatine in fermented foods. Frontiers in Microbiolgy. 2012 Jun 7;3:199. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369198/ Gadkari TV, et al. Agmatine induced NO dependent rat mesenteric artery relaxation and its impairment in salt-sensitive hypertension. Nitric Oxide. 2013 Aug 29;35C:65-71 http://www.ncbi.nlm.nih.gov/pubmed/23994446 Sidney M. Morris Jr. Arginine Metabolism: Boundaries of Our Knowledge Journal of Nutrition June 2007 vol. 137 no. 6 http://jn.nutrition.org/content/137/6/1602S.long Link to table of Agmatine content in foodstuffs http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369198/table/T1/ Piletz JE, et al. Agmatine: clinical applications after 100 years in translation. Drug Discov Today. 2013 Sep;18(17-18):880-93 http://www.ncbi.nlm.nih.gov/pubmed/23769988 Pinthong D, Hussain JF, et al. Comparison of the interaction of agmatine and crude methanolic extracts of bovine lung and brain with alpha 2-adrenoceptor binding sites. British Journal of Pharmacology. 1995 June; 115(4) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1908502/pdf/brjpharm00187-0147.pdf Also here is a nice review of the evidence from a very good site: http://examine.com/supplements/Agmatine/

Honest Supplement Review #2 [WARNING: Graphic Ending]

Honest Supplement Review #2 [WARNING: Graphic Ending]

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The Truth Behind This "Supposed" Nitric Oxide Booster | Straight Facts

The Truth Behind This "Supposed" Nitric Oxide Booster | Straight Facts

If you are paying attention to bodybuilding and food supplements you have probably heard of agmatine. An ingredient found in supplements that claim to help boost nitric oxide - but does amgatine actually help with nitric oxide levels at all? And should you be spending extra money (or maybe just your time) seeking out supplements with this ingredient? The short answer is no - and there's a very good reason why. Watch Jerry Brainum's latest episode of Straight Facts and find out why agmatine does less than nothing for your gains. Bodybuilding, fitness, weight training - all on the Generation Iron Fitness Network! Try our GYMOJI bodybuilding emojis on the app store: https://appsto.re/us/oyBLdb.i Be sure to subscribe to receive updates from the GI Fitness Network: http://www.youtube.com/subscription_center?add_user=GenerationIron Check out our official website: http://www.generationiron.com/ Check out our Facebook: https://www.facebook.com/GenerationIron And follow us on Twitter: https://twitter.com/GI_Fitness

Agmatine - latest muscle pump ingredient, promising therapy for spinal nerve pain and depression

Agmatine - latest muscle pump ingredient, promising therapy for spinal nerve pain and depression

Agmatine is an exciting ingredient. It's showing great promise as a powerful muscle pump inducing pre-workout inclusion, and it only requires a 0.5 gram dose unlike Citrulline Malate, another vasodilator that needs 8 grams! Perhaps more interesting to some people is the preliminary evidence that it can alleviate nerve pain for people with spinal disc injuries. Agmatine is even demonstrating potential as an anti-depressant. In one study 3 people with depression experienced total remission of their symptoms. Agmatine is definitely one to watch. Blog: https://www.researchedsupplements.com/agmatine Facebook: https://www.facebook.com/ResearchedSupplements/ Pinterest: https://www.pinterest.com/researchedsupplements/ Instagram: https://www.instagram.com/researchedsupplements/ Google+: https://plus.google.com/u/0/112335446744776482448

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